体重指数增加的男性容易不孕

MarkkuSallmen他在芬兰职业卫生研究所工作。他说：数据显示，男性体重每增加20磅（约9公斤），不孕的可能性就会增加10%。体重指数是由人们的体重和身高计算的数据。对大多数人来说，体重指数可以成为肥胖的可靠指标，通常用于筛查超重。

研究人员研究了农业卫生研究计划中注册的夫妇。该计划始于1993年，旨在检测影响农业社区农民及其家庭健康的因素。

国家环境卫生科学研究所流行病学家DonnaBaird医生说：与体重正常的女性相比，超重或肥胖的女性更难怀孕，但没有人研究况下男性是否有生育问题。这一结果发表在2006年9月的《流行病学杂志》上。

不孕症和体重指数的数据来自1468名农民和他们的妻子在注册时完成的问卷调查。后者完成了家庭健康调查表，包括夫妇的生育史，前者报告了家庭的体重和身高调查表。研究分析仅限于计划在注册前4年分娩和妇女年龄小于40岁的夫妇。

研究人员将这些夫妇分为不育组和可育组。一年以上未受孕者分为不育组，一年内受孕者分为可育组。大多数男女30岁以上，28%的夫妇有不孕症状。

研究人员发现，男性的体重指数是不孕症的独立危险因素。研究人员调整了其他影响生育能力的因素，如女性的高体重指数、年龄、吸烟、饮酒和接触杀虫剂。调整后，随着体重指数的增加，不孕症呈线性增加，肥胖男性的不孕率增加了一倍。研究人员还发现，男性的体重指数是不孕症的危险因素，无论年龄如何。

虽然没有频率数据，但据推测，超重男性比正常男性少，从而影响生育能力。然而，对精子特性的研究发现，超重和肥胖男性精子质量低，激素失衡。

国家环境卫生科学研究所主任DidA.Schwartz医生说：这项研究提出了其他与肥胖有关的健康问题。抑制肥胖可以促进男性的健康，包括他们的生殖健康。该研究所还提出了一项新的战略计划——环境科学和人类健康的新前沿，该计划将于明年5月实施，旨在利用环境卫生科学促进公众了解疾病的原因，促进人类健康。

Menwithincreasedbodymassindex(BMI)weresignificantlymorelikelytobeinfertilethannormal-weightmen,accordingtoresearchconductedattheNationalInstituteofEnvironmentalHealthSciences(NIEHS),oneoftheNationalInstitutesofHealth."Thedatasuggestthata20-poundincreaseinmen'sweightmayincreasethechanceofinfertilitybyabout10percent,"saysMarkkuSallmen,leadauthoronthepaperwhoisnowattheFinnishInstituteofOccupationalHealth.BMIisanumbercalculatedfromaperson'sweightandheight.BMIprovidesareliableindicatorofbodyfatnessformostpeopleandisusedtoscreenforweightcategoriesthatmayleadtohealthproblems.TheresearchersstudiedcouplesenrolledintheAgriculturalHealthStudy(AHS),alargeprojectthatbeganin1993examiningfactorsthatimpactthehealthoffarmersandtheirfamiliesinagriculturalcommunities."Womenwhoareoverweightorobesetendtoheamoredifficulttimebecomingpregnantthannormal-weightwomen,butwhethermenwhoareoverweightorobesealsohefertilityproblemshadnotbeenstudied,"saysDonnaBaird,Ph.D.,anNIEHSepidemiologistwiththestudy.ThestudyispublishedintheSeptember2006issueofEpidemiology.Thedataoninfertilityandbodymasscamefromquestionnairesthat1,468farmersandtheirwivescompletedwhentheyenrolledinthestudy.Thewivescompletedafamilyhealthquestionnaire,whichincludedinformationaboutthecouple'sreproductivehistory.Themenreportedtheirweightandheightonaquestionnaireabouttheirhealth.Theysiswaslimitedtocoupleswithapregnancyattemptduringthefouryearsbeforeenrollment,andtowomenundertheageof40.Theresearchersdividedthecouplesintoinfertileandfertilegroups.Theinfertilecoupleswerethosethattriedforlongerthanayeartoconceive,andthefertilecoupleswerethosethatconceivedwithinayear.Themajorityofmenandwomenweremorethan30yearsold.Twenty-eightpercentofthecoupleshadexperiencedinfertility.Researchersfoundthatmen'sBMIwasanindependentriskfactorforinfertility.Theresearchersadjustedforotherfactorsthatcouldaffectfertility,includinghighBMIofthewoman,age,cigarettesmoking,alcoholintake,andsolventandpesticideexposure.Afteradjustment,therewasageneralincreaseininfertilitywithincreasedBMI,reachinganearly2-foldincreaseamongobesemen.Whenresearchersdividedthesampleintotwoequalgroupsbymen'sage,theyfoundthatmen'sBMIwasariskfactorforinfertilityinboththeolderandyoungermen.Theresearchersdidnothedataonfrequencyofsexualintercourse,soitispossiblethatoverweightmenhelesssexualintercoursethantheirnormalweightcounterpartsandthiscouldinfluencefertility.However,therehebeenrecentstudieslookingatsemencharacteristicsthatshowlowersemenqualityforoverweightandobesemen,aswellashormonaldifferences."Thisstudyprovidesdataonsomeadditionalhealthproblemsassociatedwithobesity,"saidDidA.Schwartz,M.D.,directoroftheNationalInstituteofEnvironmentalHealthSciences."Preventingobesitycanhelpimprovemen'soverallhealth,perhapseventheirreproductivehealth."TheNIEHSunveiledanewstrategicplan,"NewFrontiersinEnvironmentalSciencesandHumanHealth,"inMayaimedatchallengingandenergizingthescientificcommunitytouseenvironmentalhealthsciencestounderstandthecausesofdiseaseandtoimprovehumanhealth.来源于

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